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Background

 

Growth Strategies

Our business strategy is twofold:

- to develop selected proprietary products, funding them through the preliminary phases of regulatory review before entering partnerships to share costs and to earn a share of future profits; and

- to license our proprietary technologies to corporate partners after the successful completion of reimbursed feasibility studies to earn research and development fees, licensing fees, milestone payments and royalties.

Clinical Targets
Chemotherapy-induced nausea and vomiting; post-surgical pain management, anti- inflammation, device coatings, ophthalmology andDNA/RNA orthopedic applications.

Accomplishments

Topical Parenteral
U.S. launch of Carac (5-FU)
Additional collaborations and
completion of efficacy/toxicology studies.
U.S. launch of Retin-A Micro (0.1%)
Complete Phase 2 clinical trial for APF112
Canadian launch of Retin-A Micro (0.1%) Complete Phase 1 clinical trial for APF530
U.S launch of Retin-A Micro(0.04%) Initiate Phase 2 clinical trial for APF530
   

In January 2006, we completed the sale of our rights to royalties on sales of Retin-A Micro® and Carac® for up to $30 million. We received proceeds of $25 million upon the closing of the transaction and we are entitled to receive an additional $ 5 million based on the satisfaction of certain predetermined milestones.

Condensed Statements of Operations

Three Months Ended NineMonths Ended
  9/30/2006 9/30/2005 9/30/2006 9/30/2005
Royalties 0 $1,334,000 0 $3,803,000
Total revenues 0 $ 1,337,000 0 $3,947,000
Research & Development $ 3,118,000 $ 2,306,000 $10,443,000 $7,205,000
Net income (loss) $(3,817,000) $(4,744,000) $10,932,000 $(5,607,000)
Net income (loss) per share from continuing operations $( 0.15) $ (0.07) $0.43 $(0.22)
         

 

Condensed Balance Sheets

9/30/2006
Cash, cash equivalents and marketable securities $18,073,000  
Total assets $19,949,000  
Shareholders' equity $17,530,000  


"Collaboration with corporate partners will help fund development and commercialization efforts."